ABSTRACT
No presente estudo apresentamos os diversos procedimentos terapêuticos existentes com o intuito de obter-se proteção e melhoria dos danos induzidos por radioterapia e quimioterapia no aparelho genital feminino.
The aim of this study is obtain a convenient analysis of different therapeutic methods to improve better conditions before and after radiotherapy and chemotherapy in the female genital apparatus.
Subject(s)
Humans , Female , Cryopreservation , Genital Diseases, Female/drug therapy , Genital Diseases, Female/radiotherapy , Genital Diseases, Female/therapy , Genitalia, Female/radiation effects , Radiation Injuries/prevention & control , Oocytes , Tissue Preservation/methods , Drug Therapy/adverse effects , Radiotherapy/adverse effects , Gonadotropin-Releasing Hormone/antagonists & inhibitors , Pentoxifylline/therapeutic use , Tocopherols/therapeutic useABSTRACT
O tratamento de diversos tipos de câncer poderá muitas vezes condicionar as pacientes a redução no seu potencial reprodutivo. As pacientes com diferentes neoplasias deverão ser informadas das opções terapêuticas e também das medidas necessárias para preservar sua fertilidade, dos possíveis danos no aparelho reprodutor feminino e das possibilidades futuras quanto à reprodução, antes de receberem qualquer orientação terapêutica. Esse foi o propósito deste estudo.
Treatment of several types of cancer, in many cases, lead to a reduction of the patients' reproductive potential. Such patients must be informed of different therapeutic options and possible resulting damage to the female reproductive tract, as well as all measures necessary for preserving their fertility and future possibilities to reproduce, prior to receiving any therapeutic orientation geared toward this goal. This was the basic purpose of this study.
Subject(s)
Humans , Female , Genital Diseases, Female/drug therapy , Genital Diseases, Female/radiotherapy , Genitalia, Female , Genitalia, Female/radiation effects , Maternal Age , Ovary , Ovary/radiation effects , Primary Ovarian Insufficiency , Drug Therapy/adverse effects , Radiotherapy/adverse effects , Abnormalities, Drug-InducedABSTRACT
A total of 846 Pap smears in women post-treated for genital organ diseases by operation and radiation (1.7% of all those made) at the Cytological Unit, Department of Obstetrics & Gynaecology, Faculty of Medicine, Siriraj Hospital between April 4, 1983 and July 4, 1984, were examined. The women were aged 21-75 years (mean age 43.1 +/- 9.7 years). Sixty-seven point two per cent of the women had Wertheim operations and 30.1 per cent total abdominal hysterectomies, due to invasive carcinoma (68.1% of cases) and carcinoma in situ of the uterine cervix (15.2%). Cytological findings revealed 72.8 per cent normal smears, 26.0 per cent infections (17.7% with mixed bacteria), one case of carcinoma in situ and one case of postirradiation dysplasia (both cases were post Wertheim operation). Hormonal conditions were 53.2 per cent in early menopause, 11.7 per cent in crowded menopause, 11.9 per cent in late menopause and 23.2 per cent had no hormonal evaluation. Pap smears of women post-treated for genital organ diseases by operation and radiation were examined for consideration of treatment of choice.